Senior Scientist for DSP/Filtration for AAVs, BE

Reference: JM250321R

Expiry Date: 02-11-2021

Categories Biotech, Manufacturing / Production

Salary: Competitive

Job Type: Contractor


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Job Description

Senior Scientist for DSP/Filtration for AAVs, BE

Relocation: This role is in Belgium and comes with full relocation. If Covid still runs, they will bring you over and you will initially work from a temporary apartment until you find your own place, at their expense and cost. You will benefit from a relocation package which includes tickets, logistics, removals and a settling in allowance. The Hiring and On-Boarding process is done online.

About this Opportunity

My team and I would like to let you know about this very interesting position as it is working on novel AAVs, for a well-established R&D Biotech based in Belgium. They already have established marketed products and the AAVs are a new direction for the company.

They are bringing their first VVs into clinic phases and are building their MS&T team, so there are plenty of opportunities to grow and learn!

The most exciting part of this role is that you will be part of the team that holds accountable for the development and production of AAV gene therapy assets and you will design and execute chromatography and filtration studies, and develop the final AAVs’ Down Stream Processes development around filtration and purification.

It is a great opportunity to get into the platform at the beginning and make a bigger impact on the strategy and processes by supporting the pre-clinical and clinical manufacturing as well as the definition of this DSP processes for the manufacturing facility.

You will be as the scientific SME for the DSP team internally, cross-functionally and with the CDMOs.

Your Experience & Skills

Act as a downstream process development technical subject matter expert for AAV gene therapy products supporting facility design, Quality-by-Design (QbD) process development, and pre-clinical and clinical manufacturing.

Collaborate with internal cross-functional laboratories and external CDMOs.

Design and execute chromatography and filtration studies for development of processes supporting First in Human studies through commercialization for AAV gene therapy products.

Author & review technical documents including CMC regulatory sections, process descriptions, study designs, SOPs, technical position papers, & technical reports.

Identify, evaluate, and implement new technologies to improve and refine the AAV purification platforms.

Our client is looking for a professional who has MSc or PhD in Biology/Biochemistry, Chemical/Bioengineering or Virology with a minimum of 3 years of experience in a GMP environment with solid knowledge on DSP techniques such as TFF, NFF and Chromatography.

Good understanding in English both spoken and written is mandatory, and in French would be desirable.

Package & Benefits

The role is based in Belgium and they do provide a relocation support program, digital hiring process during Covid and temporary housing with a disturbance allowance and a really decent package with 48 days off a year!

To Apply!

To apply for this role, please contact Javier Monfort on +44 (0)207 801 3385 or send a full CV to in full confidence to receive more details on this role or to hear about other available opportunities. Alternatively, press the red “Apply for position” button and follow the registration process.

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